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RTS-1C is personal bioreactor which utilize patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation where cell suspension is mixed by the singleuse falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a near-infrared optical system it is possible to register cell growth kinetics non-invasively in real time.

  • Reverse–Spin® mixing principle in 50 ml falcon tubes allows to achieve high kLa (h-1) up to 450 which is essential for efficient aerobic cultivation
  • Individually controlled bioreactor accelerates optimization process
  • Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions)
  • Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
  • Near-infrared optical system makes it possible to register cell growth kinetics
  • Free of charge software for storage, demonstration and analysis of data in real time
  • Compact design with low profile and small footprint for personal application
  • Temperature control for bioprocess applications
  • Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
  • Task profiling for process automatization
  • Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone

Software features:

  • Real–Time cell growth logging
  • 3D graphical representation of OD or growth rate over time over unit
  • Pause option
  • Save/Load option
  • Report option: PDF and Excel
  • Connect up to 10 units simultaneously to 1 computer
  • Remote monitoring option (requires internet connection)
  • Cycling/Profiling options
  • User manual calibration possibility for most cells

Typical applications:

  • Fermentation real time growth kinetics
  • Clone candidate screening
  • Protein expression
  • Temperature stress and fluctuation experiments
  • Media screening and optimization
  • Growth characterization
  • Inhibition and toxicity tests
  • Strain quality control


Measurement range 0–10 OD at 10–20ml volume (0–19 OD λ600 nm equivalent)
0–8 OD at 20–30ml volume (0–15.2 OD λ600 nm equivalent)
Measurement precision ±0.3 OD
Light source NIR Light diode
Measurement wavelength (λ) 850 nm
Measurement periodicity per hour 1–60
Cultural media volume 10–30 ml
Temperature setting range +4°C ... +70°C
Temperature control range 15°C below ambient ... +70°C
Temperature stability ±0.1°C
Display LCD
Speed control range 50–2,000 rpm
Max. number of units connected to the software 10
Type of tube for aerobic cultivation 50 ml tube with membrane filter (TubeSpin® Bioreactor 50, TPP®)*
Type of tube for anaerobic cultivation 50 ml tube with membrane filter (TubeSpin® Bioreactor 50, TPP®)*
* — it is also possible to use other manufacturer tubes of the same type, e.g. Corning® 50ml Mini Bioreactor, but the device rotor must be modified. It is possible to request this modif.
Minimum PC requirements Intel/AMD Processor, 1 GB RAM Windows Vista/7/8/8.1/10/11, USB 2.0 port
Optimal PC requirements Intel/AMD Processor, 3 GB RAM Windows Vista/7/8/8.1/10/11, USB 2.0 port
Overall dimensions (W×D×H) 130 × 212 × 200 mm
Weight 2.2 kg
Input current/power consumption 12 V, 5 A / 60 W
External power supply Input AC 100–240 V, 50/60 Hz; Output DC 12 V
  • Cat. Nr.
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    Including TPP TubeSpin® Bioreactor vessels 50ml, 20pcs
    230VAC 50/60Hz Euro plug
    230VAC 50/60Hz UK plug
    230VAC 50/60Hz AU plug
    100VAC 50/60Hz US plug, 120VAC 60Hz US plug
    IQ OQ document
    PQ document
  • 50 ml tubes with membrane filter TubeSpin® Bioreactor 50, TPP® 20 pcs.

    50 ml tubes with membrane filter TubeSpin® Bioreactor 50, TPP® 180 pcs.

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