Description

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RTS-8 is a personal bioreactor that utilizes patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation where cell suspension is mixed by the single-use falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a near-infrared optical system it is possible to register cell growth kinetics non-invasively in real time.

FEATURES

  • Parallel cultivation of 8 tube bioreactors enables to save time and resources for bioprocess optimization
  • Individually controlled bioreactor accelerates optimization process
  • Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions)
  • Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
  • Near-infrared optical system makes it possible to register cell growth kinetics
  • Free of charge software for storage, demonstration and analysis of data in real time
  • Compact design with low profile and small footprint for personal application
  • Individual temperature control for bioprocess applications
  • Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
  • Task profiling for process automatization
  • Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone

SOFTWARE FEATURES

  • Real–Time cell growth logging
  • 3D graphical representation of OD or growth rate over time over unit
  • Pause option
  • Save/Load option
  • Report option: PDF and Excel
  • Remote monitoring option (requires internet connection)
  • Cycling/Profiling options
  • User manual calibration possibility for most cells

TYPICAL APPLICATIONS

  • Fermentation real time growth kinetics
  • Clone candidate screening
  • Protein expression
  • Temperature stress and fluctuation experiments
  • Media screening and optimization
  • Growth characterization
  • Inhibition and toxicity tests
  • Strain quality control
  • Initial bioprocess optimization studies

Specification

Light source Laser
Measurement wavelength (λ) 850 ± 15 nm
Measurement range 0-100 OD600
E.coli factory calibration measurement range 0-50 OD600
P.pastoris factory calibration measurement range 0-100 OD600
Achievable user calibration measurement error (range 0.1-3 OD600) ± 0.3
Achievable user calibration measurement error (range 3-100 OD600) ≤ 15%
Measurement periodicity per hour 1-60
Temperature setting range +15°C ... +60°C
Temperature control range +15 °C below ambient ... +60 °C
Temperature stability ±0.1 °C
Sample temperature accuracy (20°C – 37°C) ±1 °C
Tube sockets 8
Sample working volume range 3–50 ml
Speed control range 50–2700 rpm
Display LCD
Dimensions (W×D×H) 350 × 690 × 300 mm
Weight 20 kg
Nominal operating voltage AC 230 V, 50 Hz
Power consumption 3.15 A / 500 W

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